When the size retains creeping up, your vitality dips regardless of sleeping eight to 9 hours, and your physique feels out of sync, but your labs come again “regular,” it’s simple to really feel such as you’re the issue.
Dr. Amie Hornaman is aware of that feeling all too effectively. She spent years competing in health and determine competitions, monitoring her macros, coaching twice a day, and doing every thing the business says ought to yield outcomes. However throughout one prep cycle in her 20s, one thing was off. Regardless of going by the books, her weight started to climb.
“I used to be following every thing completely, however I saved gaining weight, first simply 5, then 10, 15 kilos,” she informed Muscle & Health. “My coach assumed I used to be dishonest with doughnuts and pizza, however I wasn’t.”
Hornaman finally dropped out of her competitors. By then, she was additionally experiencing fatigue, mind fog, and hair loss. However when she sought assist, she says a number of physicians attributed her signs to life-style elements or stress. So she saved looking for extra solutions.
How Six Misdiagnoses Led to A Lifelong Mission
Over the course of a number of months, as she saved getting extra drained and feeling like “a shell of a human,” Hornaman says a number of docs dismissed her. “Eat much less and train extra. Cease stressing out about it,” she remembers their steering, noting “six docs misdiagnosed me, blew me off, didn’t run the proper assessments, informed me I used to be regular, informed me I used to be positive.”
It wasn’t till the seventh physician touched her throat and informed her to swallow. “I really feel a little bit one thing in your thyroid,” Hornaman recollects the physician telling her, and ordering a full thyroid panel.
She was identified with Hashimoto’s thyroiditisan autoimmune situation by which the immune system assaults the thyroid gland. She was prescribed levothyroxine (Synthroid), a normal artificial T4 medicine. “I used to be hopeful that it might assist. However after 5 months, I didn’t really feel any completely different.”
Hornaman started researching thyroid physiology and found T3, the energetic type of thyroid hormone, which her physique wasn’t changing successfully from T4. She left typical care and began working with a useful medication practitioner, who modified her medicine and added T3. Hornaman slowly started to really feel her vitality and metabolism return.
“It took six months to a 12 months to completely really feel like myself once more,” she mentioned. “However the early enhancements had been noticeable.”
That have led her to shift careers, examine useful medication, and now, because the “Thyroid Fixer,” she focuses on thyroid and hormone optimization for ladies, significantly these experiencing signs regardless of “regular” lab values.
Why Thyroid Dysfunction Is Missed in Match Ladies
Hornaman’s case isn’t uncommon. Thyroid dysfunction will be underdiagnosed, particularly in energetic girls whose signs are attributed to coaching load, stress, or age.
In response to the American Thyroid Affiliationan estimated 20 million People have some type of thyroid illness, and as much as 60% of them are undiagnosed. Moreover, girls are 5 to eight occasions extra probably than males to develop thyroid issues.
“Excessive bodily stress and low caloric consumption are recognized stressors on the thyroid,” Hornaman defined. “It may well set off or worsen circumstances like Hashimoto’s.”
In girls, thyroid points are additionally extra more likely to floor during times of hormonal change, together with postpartum, perimenopause, and menopause.
Understanding ‘Thyropause’ and Midlife Hormonal Shifts
Hornaman coined the time period “thyropause” to explain thyroid adjustments that emerge throughout midlife however are sometimes overshadowed by perimenopause.
“Hormonal fluctuations are stressors. In girls over 40, these stressors can activate underlying thyroid dysfunction, particularly if there’s a household historical past or prior immune points,” she famous.
Signs like fatigue, weight achieve, slowed restoration, and cognitive adjustments can seem in each perimenopause and hypothyroidism, making prognosis extra complicated.

Convey a Record to Your Physician’s Go to
Hornaman defined that normal thyroid testing typically contains solely TSH (thyroid-stimulating hormone), which can not detect early or subclinical dysfunction. Therefore, she encourages her sufferers to request a complete panel that features free T3, free T4, reverse T3, and thyroid antibodies.
“TSH is a mind hormone, not a thyroid hormone,” she mentioned. “It provides a part of the image, however not the complete story.”
She recommends sufferers deliver a written listing of signs and particular lab requests to appointments. “In case your supplier gained’t get them organized or tells you they’re pointless, search a second opinion.”
In response to a 2021 examine in Frontiers in Endocrinology, affected person dissatisfaction with thyroid care is frequent and infrequently linked to gaps in testing, remedy choices, and communication.
Why T3 Issues
Levothyroxine (T4) is the usual first-line remedy for hypothyroidism. However Hornaman explains, like her, many sufferers are usually not in a position to effectively convert T4 into T3, the energetic hormone. Analysis stays blended on whether or not mixture remedy is superior, however medical tips acknowledge that some sufferers might profit from a T4/T3 mixture.
“In my clinic, 100% of my sufferers want T4 and T3 or T3 solely,” Hornaman famous. “Zero does effectively on T4 solely as a result of it’s the inactive thyroid hormone.”

Life-style Issues for Thyroid Well being
Hornaman emphasizes that medicine is just one a part of managing thyroid operate. Diet, sleep, stress, and coaching load all have an effect on the stability of these hormones.
She highlights a couple of key vitamins which can be concerned in thyroid operate, similar to iodine, selenium, magnesium, and vitamin D. For girls with autoimmune thyroid circumstances, decreasing irritation can also enhance signs. She says black cumin seed oil, for instance, has been studied for its position in reducing thyroid antibody ranges.
For Hornaman, thyroid hormone substitute is a lifelong answer. “You would need to pry my thyroid hormone medicine out of my lifeless palms earlier than I truly ever stopped it,” she mentioned. “It provides me life.”
She typically compares it to insulin for kind 1 diabetes. “After we’re changing a hormone that’s not being correctly made by your physique, you may’t simply cease. When you do, you’ll go proper again into that low hormonal state.”
She additionally factors out that thyroid hormone isn’t a band-aid, however a foundational remedy that may make different drugs pointless. “As an alternative of needing an antidepressant, a statin, or a sleeping capsule, we deal with the thyroid. After which, rapidly, the melancholy lifts, ldl cholesterol improves, sleep returns, and metabolism begins to operate once more.”
Her upcoming e-book, The Thyroid Repair, is due out in Might and goals to coach girls on navigating thyroid well being with knowledge, context, and company. It’s a information to understanding how thyroid hormones have an effect on your complete physique, and what to do when normal care doesn’t go far sufficient.
“You may’t assume that ‘regular’ means optimum,” Hornaman mentioned. “It’s a must to know what good seems like, and have the instruments to ask the proper questions.”
